Volume 2, Number 2 (9-2016)                   rsj 2016, 2(2): 32-40 | Back to browse issues page


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Hasanpour Z, Amiri F. Anti-Tumor Effects of Resveratrol in Breast Cancer. rsj. 2016; 2 (2) :32-40
URL: http://rsj.iums.ac.ir/article-1-43-en.html

Abstract:   (417 Views)

Breast cancer is the most common cancer in women worldwide. Current cancer treatments have multiple side effects, including damage to healthy cells, drug resistance and disease recurrence. Therefore, new therapeutic strategies are needed to achieve fewer toxicity and side effects.

Several studies suggest that phytochemicals could be considered as appropriate choices for cancer prevention and treatment. Resveratrol (trans-3,5,4-trihydroxystilbene) is a polyphenol found in many plant species such as grapes, raspberries, mulberries, peanuts and blueberries, containing a wide range of health benefits. Resveratrol not only induces apoptosis of tumor cells and inhibits inflammatory factor NF-κB, but also inhibits some of estrogen-receptor isoforms and prevents the progression of cancer.

Therefore, based on the available studies, resveratrol can be considered as one of the most promising candidates for cancer prevention and treatment and could be used after further investigations.

Full-Text [PDF 454 kb]   (138 Downloads)    
Type of Study: Research | Subject: Special
Received: 2016/07/2 | Accepted: 2016/09/13 | Published: 2016/09/13

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