Rahavard Salamat Journal

Abstract

Introduction and objective: due to the lack of enough research on the biological effects of ALA on diabetes on the one hand, and due to the lack of any study carried out in Iran on the relationship between the amount of ALA and the possibility of suffering from Diabetes 2, the present study is an attempt to perform a systematic review on cohort studies.

Materials and methods: in this study, some search engines such as PUB MED, Scopus, and Science Direct were used to investigate cohort studies in adults. Furthermore, in order to support the results of the systematic review, a manual review was done where the references of the existing articles were checked. In case of finding any related article, it was also used in this study. 

Results: among those studies where ALA erythrocyte membrane phospholipid and plasma Cholesterol esters were measured, in three ones, there was an opposite relationship between the increasing amount of ALA and the possibility of suffering from Diabetes but in two other studies, no significant relationship was seen. Moreover, there was no significant relationship between the possibility of suffering of Diabetes and dieting measures. Even in one study, it was seen that the increase of ALA dieting measures increased the possibility of Diabetes. 

Conclusion: the present results show that fish usage might have a slight positive relationship with Diabetes 2 but more ALA usage decreases the possibility of suffering from this disease.